Carpal Tunnel Syndrome in Association with Klippel-Trénaunay Syndrome: A Case Report

Klippel-Trénaunay syndrome is a rare congenital condition that rarely affects peripheral nerves. Median nerve involvement at carpal tunnel level has only been reported in a few   occasions in the medial literature. A 61 years old Caucasian female patient with Klippel-Trénaunay syndrome presented with a 10 months history of paraesthesiae and numbness affecting the median nerve distribution area of her left hand. Clinical and neurophysiological examination confirmed a moderately severe carpal tunnel syndrome that required surgical decompression. Perioperative findings demonstrated diffuse vascular infiltration and ingurgitation of the median nerve involving its entire exposed segment. Flexor tendons had a normal appearance. Patient had a satisfactory post-operative period with full resolution of her symptoms four weeks after the procedure. Although peripheral nerves are rarely affected in patients with Klippel-Trénaunay syndrome, neurological symptoms could indicate nerve involvement and a magnetic resonance imaging (MRI) examination should be considered to further assess the extension of the lesion.